The SCCA Pharmacokinetics Laboratory (PK Lab) is a CAP/CLIA-certified clinical lab that provides therapeutic drug monitoring (TDM) services. We specialize in busulfan TDM, providing individualized drug exposure targeting for patients from over 75 medical institutions in the U.S. and Canada.
Therapeutic drug monitoring (TDM) is the specialized measurement of drug concentrations for medications with a narrow therapeutic window. Drug concentrations are used to assess and adjust medication dosage to optimize therapeutic effectiveness while minimizing adverse effects.
What do we offer?
Our lab provides individualized drug exposure targeting for patients from the SCCA Clinic, University of Washington Medical Center (UWMC), Seattle Children's and the Veteran's Affairs Medical Center in Seattle. In addition, the laboratory provides TDM services to physicians from other medical institutions throughout the U.S. and Canada. We collaborate with providers and researchers throughout the country, as well as our alliance partners on clinical research protocols related to PK/PD/pharmacogenomics of various oncology-related agents.
Under specific arrangements via contracting, the PK Lab also provides analytical services for clinical trials or studies from the pharmaceutical industry, government entities and other institutions for research and/or clinical purposes.
Our expertise includes:
- Study design and protocol development
- Grant writing
- Assay development/validation
- Data management/analysis
- Manuscript preparation/publication
Our current analytical equipment:
- Five GC-MS analytical systems
- One triple quadrupole LC/MS system
Why use our services?
One-stop service for busulfan targeting: We offer a complete package of services from sample concentration analyses to dose recommendations. As physicians receive our reports, they will be ready to administer the next dose with greater confidence.
Fast turnaround time: Subsequent dose recommendation and busulfan level results are usually available on the same day of the sample’s arrival on-site. A verbal report is delivered by direct telephone communication with the attending physician and/or clinical pharmacist. Then a formal hard-copy report is faxed to designated recipients.
Professional consultation is always available: A pharmacokinetics specialist is always available to answer care provider questions.
- Well-trained staff with extensive experience: We have more than 15 years of experience in busulfan TDM. Every staff member is professionally trained in related scientific or medical fields.
Seattle Cancer Care Alliance Pharmacokinetics Lab
Lab Hours: Tuesday to Saturday, 8 am to 5 pm
Lab closed on Sundays, Mondays and holidays
Office: (206) 606-7389
Fax: (206) 606-7397
Pager: (206) 994-5942
Please send samples to:
Seattle Cancer Care Alliance
188 E Blaine Street, Suite 250
Seattle, WA 98102
Sending Busulfan Samples
This page is designed for referral institutions only.